Monday, December 29, 2025

Hemostatic Agents to Stop Bleeding

Disclaimer.  I am not a licensed health practitioner.  This is just another post on knowledge and understanding you might wish to acquire in advance of a disaster in case no higher care is available.  As long as our society is functioning, you should leave anything more substantial than applying a Band-Aid to the professionals.  No medication, including those available over the counter, should be taken without consulting a physician.  Information shared here is for educational and entertainment purposes only.  It is not medical advice nor a substitute for licensed medical care. 

When faced with treating life-threatening bleeding, military medics have turned to hemostatic agents for years. In conjunction with direct pressure, they stop bleeding in places where tourniquets cannot be used, especially the head, neck, abdomen and pelvic area. Celox and Quikclot have been around for years; X-Gauze is the new kid on the block.  

While initially designed for military use, all three products are available to civilians without restriction. Celox and Quikclot can be found in stores and online, but for X-Gauze, you've got to go to their website.  

These clotting agents are sold as granules, z-pack gauze, and sponges. The granules are poured onto or into a wound. But if that wound is still spurting blood, the granules are going to be washed away. The clotting agent must be exactly where the blood is coming from to be of any use.  

Z-pack gauze is favored for most applications. The gauze is impregnated with the clotting agent and can be packed very tightly against an internal wound. The clotting agent cannot be washed away. And the medic using this product does not have to bother with packing the wound while simultaneously sprinkling in the clotting agent. 

All three products differ in their mechanism of action. QuikClot uses kaolin, a natural clotting agent that accelerates the body's natural clotting abilities. When used in conjunction with direct pressure, it stops life-threatening bleeding within five minutes. It has a five-year shelf-life from the date of manufacture. QuikClot and the kaolin and gauze must be completely removed from the body before the wound is closed.

Celox uses chitosan, a clotting agent derived from shrimp. Throughout extensive clinical trials and field use, there have been no reports of any allergic reactions, even among individuals allergic to shellfish or iodine. Like QuikClot, Celox stops severe bleeding within five minutes when used together with direct pressure. Unlike the kaolin in Quikclot, the chitosan in Celox can be broken down by the body. So while it should be thoroughly washed away before the wound is closed, chitosan is less likely to cause a problem if small amounts are not removed. Celox granules have a four-year shelf-life. Like QuikClot, Celox gauze has a five-year shelf-life from the date of manufacture.  

Both of these products work to clot blood even in patients taking blood thinners, as well as in cases where hypothermia is an issue.  

X-Gauze, in contrast, does not use a hemostatic clotting agent. Instead, it is gauze impregnated with miniature sponges that expand to ten times their size on contact with fluids to stop bleeding by direct pressure. It is ideal in that it conforms to the wound perfectly and exerts pressure everywhere. As of this writing, it is not available on Amazon; you have to go to their website. Because it is new, it does not have extensive field testing, but clinical trials have shown that it is a very promising technology. Unfortunately, at $50 each, they're a little expensive right now.  

It must be emphasized that none of these clotting agents substitute for direct pressure. Direct pressure will stop the vast majority of bleeding within thirty minutes. If direct pressure fails to stop bleeding after thirty minutes (without peeking every five minutes to check, which may interrupt any clotting that started), then a clotting agent and/or tourniquet may be required. 

Links to related posts:
Bleeding
Tourniquets 

For further reading:
https://pdfs.semanticscholar.org/5742/31fb7a3bb1fa973113958a9de48a4a6a8f9b.pdf
https://www.celoxmedical.com/eur/eurfaq/
https://quikclot.com/QuikClot/Clinical-Evidence
https://www.revmedx.com/xgauze/

 14 january 2020

6 comments:

  1. Snip: Cayenne is a Hemostat, arresting the flow of blood from a cut or wound in seconds and a cardiac tonic, helping to rebuild the heart. And cayenne is a Stomachic, helping to digest foods and a Carminative, helping to expel gas.

    I cannot grow those other hemostats, but I can grow peppers for spices and health :-)

    ReplyDelete
    Replies
    1. Love cayenne. Got a post or two on it here. Cayenne tincture has quite a bit of anecdotal evidence showing it helps stop/reverse heart attacks and strokes. I carry a small bottle of the tincture in my bag.

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  2. Plain black pepper works on wounds. I'm not sure what it would do for a major or deep wound. I have used it on smaller wounds. It causes clotting in seconds. Don't believe me, the next time you get a small cut dump some on it. You'll become a believer!

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  3. SeraSeal™ is the World’s ONLY Primary Hemostatic Agent, that stops major hemorrhages in seconds.
    SeraSeal™ represents a new generation of medical device, in the form of technology which improves surgical efficiency, reduces cost and dramatically impacts patient outcomes. It is time, both ethically and economically, to usher in this new method of patient care from the outset of injury through the path of surgery and post-op care. SeraSeal™ represents a new generation of a haemostatic product, designed to arrest the bleed within seconds, and it is effective in all forms of coagulopathy, due to anticoagulant medications, platelet inhibitors, and factor deficiency.


    To clarify your doubts and clear your misconceptions about the how this hemostatic agent can change the world for the better and save millions of life; click on the link below.
    (http://seraseal.in/?utm_medium=SeraSealSubmission&utm_source=blogger&utm_campaign=SeraSealsubmission)

    ReplyDelete
  4. However, if you happen to be carrying this around and you have medical professional assisting with the bleed, please mention you have it to start with, not after 30 minutes of trying!

    ReplyDelete

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