Showing posts with label ciprofloxacin. Show all posts
Showing posts with label ciprofloxacin. Show all posts

Wednesday, June 4, 2025

Tularemia--What's the Risk?--And School's Out!

School's Out!

I just forgot to remind you.  ;)

Just like last year, I've decided to take the summer off from writing new posts.  I need time in the garden and for selling my books at farmers markets here and in Utah.  But last summer, I couldn't keep from writing and simply built up a nice reserve of articles to carry me through the year.  These past couple of weeks, I've been trying to compose new articles--there is still so much to learn--but without much success.  Perhaps because the garden calls.  Perhaps because I feel the need to compile the medical articles into a 2nd edition of Bring Your Own Bandages.  

Of course, I will continue to re-post previous articles.  We all need to be reminded.  I'll continue to check the comments and try to respond within a day.  Or so.  It is summer, after all.

Enjoy time outdoors and with family, and keep on preparing.

 

Since at least fifth or sixth grade, maybe even earlier, I've been fascinated with infectious disease.  Yes, my family finds it creepy.  I don't know.  Am I the only one who thinks discussing smallpox or the Spanish flu or yellow fever makes for great dinnertime conversation?

But even with my interest in these dread diseases, I couldn't remember much about tularemia or even whether it was all that serious, only that it was associated with rabbits.  Ha!  At least I remembered that correctly.  Tularemia is indeed a bacterial disease associated with rodents, rabbits, and hares.  It is usually a rural disease and occurs throughout the United States, except Hawaii, though most cases occur in the south central and western states.  The mortality rate without treatment is 33%; with treatment it is less than 2%.

As with any disease, prevention is always the best way to go.  To prevent tularemia, take the following measures, only one of which is unique to this disease:

  • Use insect repellent.  Most cases of tularemia are transmitted by tick and deer fly bites.  Use DEET or something similar on the skin and permethrin on clothes.
  • Wash hands often when handling sick animals or carcasses, especially rabbits and hares.
  • Cook food thoroughly and make sure your water is pure.  
  • Note any changes in pet rabbits, rodents, and hares.  
Tularemia is unique in that the bacteria responsible for the disease can be transmitted in numerous ways.  Diagnosis is made much more difficult because the signs and symptoms vary depending on how the person was infected and where the bacteria choose to set up housekeeping.  As noted earlier, the signs and symptoms of tularemia will depend on how the person was infected.  The incubation period is generally 3 to 5 days, but may range from 1 to 14 days. Tularemia manifests in the following forms:
  • Ulceroglandular:  75% of tularemia cases are ulceroglandular and result from a tick or deer fly bite or the handling of infected animals or carcasses.  There is a single lesion at the bite site with a central eschar.  The lesion looks like other bug bites--swollen and raised, and the eschar is the actual site of the bite with the dead tissue and scab spreading out.  There is prominent lymphadenopathy (swollen glands).  The first cases identified in the United States were in Utah, and the disease, Francisella tularensis, is named for the Utah man who first researched it, Edward Francis.
  • Glandular:  This is the most common form in children.  There is regional lymphadenopathy.  The glands are swollen and painful and may need draining.  The bite may have healed over or may have been overlooked.
  • Oropharyngeal:  This form presents with a fever, severe sore throat, mouth ulcers, exudative pharyngitis, and tonsillitis.  It arises from ingesting contaminated food or water.  There is prominent lymphadenopathy around the neck, ears, and jaws.
  • Oculoglandular:  This form is marked by eye pain, including photophobia, excessive tearing, conjunctivitis, and small ulcers of the cornea.  It may result from airborne bacteria, a splash of contaminated water, or rubbing the eyes with contaminated hands.  There is prominent lymphadenopathy around the neck, ears, and jaws.
  • Intestinal:  A rare form of tularemia marked by intestinal pain, vomiting, and diarrhea.  It arises due to eating undercooked, contaminated food or drinking contaminated water.
  • Pneumonic, or pulmonary:  This form occurs due to inhalation or spread from ulceroglandular or typhoidal forms.  Farmers, sheep shearers, landscapers, and lab workers are at greater risk for this form of the disease.  Symptoms are very similar to pneumonic plague and influenza, including chest pain, dry cough, and shortness of breath.  Untreated, this form has a 30-60% mortality rate.
  • Typhoidal:  This form is difficult to diagnose.  There is little if any lymphadenopathy.  Symptoms are not specific and may include a high fever, nausea, vomiting, diarrhea, abdominal pain, cough, pneumonia.

Tularemia is unique in that there are so many ways it can be transmitted and so many forms it can take.  Fortunately, there is no documented transmission from person to person, so the patient does not need to be isolated.  However, and this may be significant to those with dogs, our pets can transmit it to us.  In a collapse scenario, our dogs may decide to start supplementing their diets with rabbits and hares.  And sick rabbits are easier to catch.  The dogs may contract tularemia and pass it to us.

What's interesting about tularemia is that it is classified as a Category A bioweapon by the CDC.  It's right up there with anthrax, smallpox, plague, and botulism.  It is easily disseminated, and very few bacteria are needed to cause illness. 

Fortunately, tularemia can be treated.  The drugs of choice are gentamicin or streptomycin, which are both intramuscularly or intravenously administered, and neither of which is commonly available to or stocked by preppers.   The other options are doxycycline or ciprofloxacin.  Physicians generally prescribe doxycycline 100 mg or ciprofloxacin 500 mg, both every 12 hours for 10-14 days.  Unfortunately, there's a good chance for relapse with both of these drugs.

Links to related posts:
TEOTWAWKI Tick Prevention  

For further reading:
https://emergency.cdc.gov/agent/tularemia/facts.asp
https://texashelp.tamu.edu/wp-content/uploads/2016/02/Tularemia-and-Bioterrorism.pdf
https://www.wikem.org/wiki/Tularemia--different clinical features of tularemia
https://azdhs.gov/documents/preparedness/emergency-preparedness/zebra-manual/zm-s4-tularemia.pdf
https://texasprepares.org/factsheets/factsheet_tularemia_and_bioterror_eng.pdf
https://www.ok.gov/health2/documents/Tularemia.pdf
http://outbreaknewstoday.com/isis-and-bioterrorism-tularemia-planned-use-in-turkeys-water-67823/
https://www.acsh.org/news/2017/08/24/dog-gives-woman-fatal-tularemia-potential-bioterrorism-agent-11741
https://academic.oup.com/cid/article/47/1/e4/378987
https://www.oregon.gov/oha/ph/DiseasesConditions/CommunicableDisease/ReportingCommunicableDisease/ReportingGuidelines/Documents/tularemia.pdf
https://www.merckmanuals.com/professional/infectious-diseases/gram-negative-bacilli/tularemia

© 2019, PrepSchoolDaily.blogspot.com    

23 june 2021

Monday, April 8, 2019

The Medicinal Uses of Rosemary

Disclaimer.  I am not a licensed health practitioner.  This is just another post on an item you might wish to have available if needed so that a physician can treat you and your family as best as possible.  No medication, including those available over the counter, should be taken without consulting a physician.  Information shared here is for educational and entertainment purposes only.  It is not medical advice nor a substitute for licensed medical care.  A qualified, licensed physician or other medical provider should be consulted before beginning any herbal or conventional treatment.

On a recent trip to Las Vegas so that my daughters could participate in some archery tournaments, we used credit card points to get a free room, which was about 20 minutes away from the event.  So we got to do a bit of driving each day, and I was really surprised to see that rosemary was an extremely popular commercial landscaping shrub, at least in the section of the city that we were traversing.  I've never seen it used commercially here in the northern part of the state, but we do have it growing in our yard, which is zone 6.  The USDA zone hardiness guidelines indicate that rosemary grows in zones 6-10. 


Rosmarinus officinalis, rosemary, is a highly medicinal member of the mint family, like its relatives oregano, thyme, lavender, and basil.  Native to the Mediterranean, this fragrant evergreen perennial herb has been used for centuries, probably millenia in cooking and perfumes, but most importantly, in medicine.  The leaves of this perennial herb can be harvested year-round. 

Medicinal uses:  Rosemary works in so many ways.  It is anti-inflammatory, increases distal circulation, relieves depression, and acts against pathogenic E. coli and H. pylori infections and urinary tract infections.  It has been shown to provide relief for irritable bowel syndrome, colitis, headaches, migraines, cirrhosis, and kidney pain, and to prevent and treat Alzheimer's and improve memory in the elderly.  But because rosemary is so diverse in its actions, there is also the potential for negative interactions with other pharmaceuticals.  A lot of people like to believe that because rosemary is natural and is a food that it is safe to take in unlimited quantities.  Rosemary most definitely is not.

Rockefeller, who is credited with saying "A pill for every ill" and who promoted our US medical school system and almost single-handedly eliminated holistic or natural medicine that had been practiced since people first started getting sick, would definitely not approve of the numerous ways rosemary can be used to relieve pain and illness.  And indeed, it is a bit of a stretch at times to learn all you can about an herb, how to grow it, how it's used, the effects it has on other systems in the body, and so on.  But it's also a blessing to be able to have a few different herbs at your disposal, just in case one can't be used because it could affect a patient adversely, whatever the reason.  Rosemary, due to its longstanding use in folk medicine, is one of those herbs that is really attracting the attention of medical researchers.  The number of studies being conducted--and the phenomenal results being reported--are astounding. (And the same could be said for many other herbs.) There is no way to discuss them all here.  So I've included links for them below.  What I discuss here will be of more general interest to preppers as a whole.

Infusion:  Two teaspoons fresh rosemary, or one teaspoon dried, steeped 10 minutes in 1 cup of boiling water.  Drink as needed to relieve colds, headaches, sore throat, indigestion, and stomach cramps.  This may also be used as a wound wash.


Essential oil: For the following conditions, mix the number of drops of essential oils indicated into a carrier oil such as coconut, almond, or olive, and massage into afflicted area of body.
  • Neuropathy--2 drops each rosemary, helichrysum, and cypress into 1/2 teaspoon carrier oil
  • Joint pain, rheumatoid arthritis, inflammation--2 drops rosemary and 2 drops peppermint in 1 teaspoon carrier oil 
  • Gall bladder issues--2 drops rosemary in 1/2 teaspoon carrier oil, twice per day
  • Wounds, bruises, sores, eczema, Raynaud's syndrome (cold hands and feet)--4 drops in 1 teaspoon carrier oil, use as needed.
Aromatherapy:  Diffuse essential oil into the room or study area to improve concentration and memory and reduce stress.  If diffusing into the air is not an option, rub 2-3 drops of rosemary oil mixed into 1/2 teaspoon of carrier oil and rub onto the neck or wrists. 

Tincture: A tincture is made with 40% alcohol (80 proof).  Pack a pint jar with fresh rosemary and top off with alcohol.  Cap and seal and put in a dark place.  Shake the jar every two or three days for six weeks.  Then strain off the rosemary and put your rosemary tincture in a dark glass bottle with a dropper.  Add 1-5 drops to a cup of boiling water to relieve cold and sore throat symptoms, headaches and migraines, and anxiety and depression.


A cursory review of scientific literature on recent research with rosemary revealed a lot of really interesting ideas.  Preliminary research shows a synergistic effect between rosemary and Tylenol-3 (acetaminophen and codeine).  It appears to work synergistically with ciprofloxacin against Klebsiella pneumoniae.  It is effective in helping opioid withdrawal pain.  And it repels ticks and mosquitoes.  If any of these topics interest you, you'll need to research them on your own.  Much of this research also includes using rosemary essential oil internally, and most everybody says that practice is not safe.  Unless it's X brand or brand.  You'll have to do your own research again and determine what is best for you.

Contraindications:  Do not use rosemary medicinally (culinary use is fine)  if you:
  • are pregnant
  • have epilepsy
  • have high blood pressure
Or if you are using:
  • anticoagulants such as warfarin or aspirin
  • ACE inhibitors
  • diuretics such as furosemide
  • lithium 
Links to related posts:
Peppermint-Lavender-Rosemary Headache Balm   
Peppermint   
Spearmint   

For further reading:
(All articles accessed 21 February 2019)
https://www.healthline.com/nutrition/rosemary-oil-benefits#section11
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749867/ (Alzheimer's)
https://www.ncbi.nlm.nih.gov/pubmed/21877951 (cognitive function in elderly)
https://www.ncbi.nlm.nih.gov/pubmed/21955093 (cancer prevention)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905473/ (opioid withdrawal)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736918/ (aroma improves cognitive performance)
https://www.ncbi.nlm.nih.gov/pubmed/25635991 (synergistic with acetaminophen and codeine)
https://ecommons.cornell.edu/handle/1813/56138 (insect repellent)
https://www.ncbi.nlm.nih.gov/pubmed/17583499 (insect repellent)
https://www.ncbi.nlm.nih.gov/pubmed/20695287 (tick repellent)
https://www.ncbi.nlm.nih.gov/pubmed/30219447 (Raynaud's syndrome)
https://www.ncbi.nlm.nih.gov/pubmed/27091583 (rheumatoid arthritis)
https://www.ncbi.nlm.nih.gov/pubmed/24287491 (effect of essential oils on bacteria)
https://www.epilepsysociety.org.uk/complementary-therapies#.W8DZvGhKiUk (epilepsy)
https://www.ncbi.nlm.nih.gov/pubmed/24269249 (hypertension)
https://aac.asm.org/content/49/6/2474 (Gram-negative bacteria more susceptible to essential oils than Gram-positive)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336450/ (cirrhosis)
https://draxe.com/rosemary-oil-uses-benefits/

© 2019, PrepSchoolDaily.blogspot.com  

22 november 2020 

1 july 2024